Tardive dyskinesia due to risperidone.

Tardive dyskinesia (TD) is a neuroleptic-induced movement disorder, and is recognised as a late adverse effect of neuroleptic drugs. We report a case of TD associated with risperidone, a new “atypical” antipsychotic drug. Risperidone has a high affinity for D2 dopamine and 5-HT2 receptors [8 1. Thus, it produces less extrapyramidal side effects (EPS) than classical neuroleptics. Also, risperidone was shown to have a beneficial effect on TD [3, 7, 91. To our knowledge, only four cases have been reported concerning the appearance of TD in relation to risperidone administration [l, 2, 5, lo].